The purpose of our research is a design of » Innovation Reference Model«. Scientific importance of the research developed on the basis of an analysis of the most successful companies may be observed in addressing all modern innovation factors. Expected concrete research results with an international relevance shall be just as important. The model shall offer a set of influence and innovation factors classified as per their importance and related with economic successfulness of a company. Research results (mathematical model) shall be upgraded with users modele, so-called "Innovation beyond numbers", which shall represent additional functional value for companies. Multi-layer model shall serve companies on strategic level and at the same time on tactical and operational level for improving their economic efficency. If companies decide to compare the state of their company with concrete values of the best companies (benchmarking), they shall be able to define their innovation strategy and objectives as well as regularly follow their progress. Beside the aforementioned, the results shall be relevant and important also for competent state institutions which may contribute to the improvement of the state by systemic measures appertaining to the research.